MMP 7 Protease Assay Service

MMP 7 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MMP7
Enzyme
MMP-7, catalytic domain from human recombinant (residues 78-250) expressed in E. coli with C-terminal tag
Synonym
Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP-7, Matrin
Substrates
(5-FAM/QXLTM) FRET peptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
NNGH4.40E-06
Actinonin2.33E-06
GM60013.66E-09
MMP Inhibitor III1.90E-08
MMP-9/MMP-13 Inhibitor I1.61E-06
Scientific Information
P09237 (http://www.uniprot.org/uniprot/P09237)
Screening Location
Malvern, USA
Reference compound IC50 for MMP-7
Reference compound IC50 for MMP-7
PDF