MMP 9 Protease Assay Service

MMP 9 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MMP9
Enzyme
MMP-9, catalytic domain from human recombinant (residues 88-438) expressed in E. coli with C-terminal tag
Synonym
MMP-9, 92 kDa type IV collagenase, 92 kDa gelatinase, Gelatinase B, GELB
Substrates
(5-FAM/QXLTM) FRET peptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
NNGH1.43E-09
Actinonin6.35E-08
GM60011.02E-10
MMP Inhibitor III3.63E-10
MMP-9/MMP-13 Inhibitor I6.79E-10
Scientific Information
P14780 (http://www.uniprot.org/uniprot/P14780)
Screening Location
Malvern, USA
Reference compound IC50 for MMP-9
Reference compound IC50 for MMP-9