MST1/STK4 Kinase Assay Service

Activity-based MST1/STK4 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
MST1

Enzyme
Human MST1

HGNC
STK4

Synonym
MST1

Substrates
Peptide substrate, [KKSRGDYMTMQIG], 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 1.1
Ro 31-8220 60
GW 5074 206
H-89 14,700
Scientific Information
Q13043 (http://www.uniprot.org/uniprot/Q13043)

Screening Location
Malvern, USA

Reference compound IC50 for MST1/STK4
Reference compound IC50 for MST1/STK4

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