MST4 Kinase Assay Service

Activity-based MST4 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
MST4
Enzyme
Human MST4
HGNC
STK26
Synonym
MASK
Substrates
MBP (Myelin Basic Protein), 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine6.7
Ro 31-8220160
GW 507414,000
Scientific Information
Q9P289 (http://www.uniprot.org/uniprot/Q9P289)
Screening Location
Malvern, USA
Reference compound IC50 for MST4
Reference compound IC50 for MST4