MYO3b Kinase Assay Service

Activity-based MYO3b kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
MYO3b

Enzyme
Human MYO3b

HGNC
MYO3B

Synonym
MYO3b

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 12.8
Ro 31-8220 130
GW 5074 91
H-89 4,800
Scientific Information
Q8WXR4 (http://www.uniprot.org/uniprot/Q8WXR4)

Screening Location
Malvern, USA

Reference compound IC50 for MYO3b
Reference compound IC50 for MYO3b

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