MYO3b Kinase Assay Service

Activity-based MYO3b kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
MYO3b
Enzyme
Human MYO3b
HGNC
MYO3B
Synonym
MYO3b
Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine12.8
Ro 31-8220130
GW 507491
H-894,800
Scientific Information
Q8WXR4 (http://www.uniprot.org/uniprot/Q8WXR4)
Screening Location
Malvern, USA
Reference compound IC50 for MYO3b
Reference compound IC50 for MYO3b