MYST2 Histone Acetyltransferase Assay Service

Activity-based MYST2 Histone Acetyltransferase Assay for compound screening and profiling via radiometric HAT assay.
CAT#
MYST2
Enzyme
Human MYST2
Synonyms
Histone acetyltransferase MYST2, Histone acetyltransferase binding to ORC1 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, HBO1, HBOa
Substrates
Histone H3, 5 μM
Acetyl CoA, 3 μM
Reaction
[Acetyl-³H]-Acetyl Coenzyme A + histone L-lysine = Coenzyme A + [Acety-³H]-L-lysine
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Anacardic Acid5,200
Garcinol11,000
Curcumin44,000
Scientific Information
O95251 (http://www.uniprot.org/uniprot/O95251)
Screening Location
Malvern, USA
Reference Compound IC50 for MYST2
Reference Compound IC50 for MYST2