MYST4 Histone Acetyltransferase Assay Service

Activity-based MYST4 Histone Acetyltransferase Assay for compound screening and profiling via radiometric HAT assay.
CAT#
MYST4
Enzyme
Human MYST4
Synonyms
Histone acetyltransferase KAT6B, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4, Monocytic leukemia zinc finger protein-related factor, KIAA0383, MORF, MOZ2
Substrates
Histone H4, 5 μM
Acetyl CoA, 3 μM
Reaction
[Acetyl-³H]-Acetyl Coenzyme A + histone L-lysine = Coenzyme A + [Acety-³H]-L-lysine
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Anacardic Acid20,000
Garcinol17,500
Curcumin14,000
Scientific Information
Q8WYB5 (http://www.uniprot.org/uniprot/Q8WYB5)
Screening Location
Malvern, USA
Reference Compound IC50 for MYST4
Reference Compound IC50 for MYST4