OPRD1 cAMP Agonist Assay for compound screening and profiling.
Target Information
Cell Catalog#
LLC-2050
GPCR Name
Human Delta-type opioid receptor
Gene Name
OPRD1
GPCR Sub Family
Opioid receptors
Coupling Partner
Gαi
Uniprot Number
P41143 (https://www.uniprot.org/uniprotkb/P41143/entry)
Cell Type
HEK293/OPRD1/β-arrestin-2 stable cell line
Assay Information
Assay Principle
The cAMP agonist assay detects agonist-induced inhibition of cAMP production via OPRD1 activation in HEK293/OPRD1/β-arrestin-2 stable cell line.
Assay Type
Cell-based functional assay
Functional Mode
Agonist
Assay Readout
FRET fluorescence
Reference Compound EC50
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website GPCR Assay and Profiling Services
Representative dose–response curve of reference agonist for OPRD1
