OPRD1 β-arrestin Agonist Assay for compound screening and profiling.
Target Information
Cell Catalog#
LLC-2050
GPCR Name
Human Delta-type opioid receptor
Gene Name
OPRD1
GPCR Sub Family
Opioid receptors
Coupling Partner
β-arrestin-2
Uniprot Number
P41143 (https://www.uniprot.org/uniprotkb/P41143/entry)
Cell Type
HEK293/OPRD1/β-arrestin-2 stable cell line
Assay Information
Assay Principle
The LinkLight™ β-arrestin agonist assay measures agonist-induced recruitment of β-arrestin-2 via OPRD1 activation in HEK293/OPRD1/β-arrestin-2 stable cell line.
Assay Type
Cell-based functional assay
Functional Mode
Agonist
Assay Readout
Luminescence
Reference Compound EC50
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website GPCR Assay and Profiling Services
Representative dose–response curve of reference agonist for OPRD1
