P38d/MAPK13 Kinase Assay Service

Activity-based P38d/MAPK13 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
P38d/MAPK13

Enzyme
Human P38d/MAPK13

HGNC
MAPK13

Synonym
p38-delta, PRKM13, SAPK4

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 730
Ro 31-8220 >20,000
Scientific Information
O15264 (http://www.uniprot.org/uniprot/O15264)

Screening Location
Malvern, USA

Reference compound IC50 for P38d/MAPK13
Reference compound IC50 for P38d/MAPK13

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