P38d/MAPK13 Kinase Assay Service

Activity-based P38d/MAPK13 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
P38d/MAPK13
Enzyme
Human P38d/MAPK13
HGNC
MAPK13
Synonym
p38-delta, PRKM13, SAPK4
Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine730
Ro 31-8220>20,000
Scientific Information
O15264 (http://www.uniprot.org/uniprot/O15264)
Screening Location
Malvern, USA
Reference compound IC50 for P38d/MAPK13
Reference compound IC50 for P38d/MAPK13