PAK7 Kinase Activity Assay Service

Activity-based PAK7 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

PAK7

Enzyme

Human PAK7, wt

HGNC

PAK5

Manning ID

PAK5

Synonym

KIAA1264, MGC26232, PAK7, PAK5

UniProt

Q9P286 (PAK5_HUMAN)

Kinase Type

Protein kinase

Kinase Group

STE

Assay Properties

Assay Format

33PanQinaseTM

Substrates

bio-4xCHKT, ATP

Reaction

bio-4xCHKT + 33P-ATP = 33P-bio-4xCHKT + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 11
Sorafenib 10000
Sunitinb 16000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice PAK7
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – PAK7
(Activity verified by 33PanQinaseTM-Assay)

Product Number

0410-0000-1

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