PASK Kinase Activity Assay Service

Activity-based PASK kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

PASK

Enzyme

Human PASK, wt

HGNC

PASK

Manning ID

PASK

Synonym

DKFZP434O051, DKFZp686P2031, KIAA0135, PASKIN, STK3, PASK

UniProt

Q96RG2 (PASK_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CAMK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-CHKtide, ATP

Reaction

RBER-CHKtide + 33P-ATP = 33P-RBER-CHKtide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 56
Sorafenib 10000
Sunitinb 85000

 

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice PASK
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number

N/A

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