pCAF Histone Acetyltransferase Assay Service

Activity-based pCAF Histone Acetyltransferase Assay for compound screening and profiling via radiometric HAT assay.
CAT#
pCAF
Enzyme
Human pCAF
Synonyms
Histone acetyltransferase KAT2B, Lysine acetyltransferase 2B, Histone acetyltransferase PCAF, P300/CBP-associated factor, PCAF, KAT2B
Substrates
Histone H3, 5 μM
Acetyl CoA, 3 μM
Reaction
[Acetyl-³H]-Acetyl Coenzyme A + histone L-lysine = Coenzyme A + [Acety-³H]-L-lysine
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Anacardic Acid41,700
Garcinol69,000
Scientific Information
Q92831 (http://www.uniprot.org/uniprot/Q92831)
Screening Location
Malvern, USA
Reference Compound IC50 for pCAF
Reference Compound IC50 for pCAF