PEAK1 Kinase Assay Service

Activity-based PEAK1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
PEAK1
Enzyme
Human PEAK1
HGNC
PEAK1
Synonym
PEAK1, KIAA2002
Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine1.9
PP219
AG1478883
PDGFR I-III>100,000
D-64406620
Scientific Information
Q9H792 (http://www.uniprot.org/uniprot/Q9H792)
Screening Location
Malvern, USA
Reference compound IC50 for PEAK1
Reference compound IC50 for PEAK1