Activity-based PI3KC2a lipid kinase assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
PI3KC2A
Enzyme
Human PI3KC2A
HGNC
PIK3C2A
Synonym
CPK, MGC142218, PI3-K-C2A
Scientific Information
O00443 (http://www.uniprot.org/uniprot/O00443)
Assay Properties
Substrates
PI, 50 µM
ATP, 10 µM
Reaction
1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| PI-103 | 460 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound IC50 for PI3KC2A
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