Activity-based PI4K2A lipid kinase assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
PI4K2A
Enzyme
Human PI4K2A
HGNC
PI4K2A
Synonym
PI4KII, PIK42A, RP11-548K23.6
Scientific Information
Q9BTU6 (http://www.uniprot.org/uniprot/Q9BTU6)
Assay Properties
Substrates
PI, 50 µM
ATP, 10 µM
Reaction
1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-bisphosphate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| PIK-93 | 37,000 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Assays
Reference compound IC50 for PI4K2A
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