PI4Ka Kinase Assay Service

Activity-based PI4Ka lipid kinase assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
PI4KA
Enzyme
Human PI4KA
HGNC
PI4KA
Synonym
PIK4CA
Substrates
PI, 100 µM
ATP 10 µM
Assay Properties
Reaction
1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-bisphosphate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
PIK-93530
Scientific Information
P42356 (http://www.uniprot.org/uniprot/P42356)
Screening Location
Malvern, USA
Reference compound IC50 for PI4KA
Reference compound IC50 for PI4KA