PIK3C2G Kinase Activity Assay Service

Activity-based PIK3C2G kinase assay for compound screening and profiling via ADP-Glo – assay technology

Target Overview

RBE Target ID

PIK3C2G

Enzyme

Human PIK3C2G, wt

HGNC

PIK3C2G

Manning ID

N/A

Synonym

PI3K-C2GAMMA,  PI3K-C2-gamma, PIK3C2G, PI3K-C2-gamma

UniProt

O75747 (P3C2G_HUMAN)

Kinase Type

Lipid kinase

Kinase Group

PI3K

Assay Properties

Assay Format

ADP-Glo

Substrates

PI:PS, ATP

Reaction

PI:PS + ATP = P-PI:PS + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Wortmannin 1400
LY294002 7700
PI-103 92

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice PIK3C2G
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon No
Lipid Kinase Profiler Addon Yes
IC50 Profiler IC50 Lipid Kinase Profiler
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – PIK3C2G
(Activity verified by ADP-Glo – Assay)

Product Number

1207-0000-1

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