Activity-based PKMYT1 kinase assay for compound screening and profiling via ADP-Glo kinase assay.
Target Overview
CAT#
PKMYT1 (ADP-Glo)
Enzyme
Human PKMYT1
HGNC
PKMYT1
Synonym
Myt1 kinase, MYT1, PMYT1
Assay Properties
Substrates
ATP, 10 µM
Reaction
ADP-Glo Detection
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 |
|---|---|
| Lunresertib (RP-6306) | 0.6 nM |
| CTX-0294885 | 45.6 nM |
| Staurosporine | >10 µM |
Scientific Information
Q99640 (http://www.uniprot.org/uniprot/Q99640)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Kinase Screening Assay Services
Reference compound IC50 for PKMYT1 (ADP-Glo)
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