PRKG2 Kinase Activity Assay Service

Activity-based PRKG2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

PRKG2

Enzyme

Human PRKG2, wt

HGNC

PRKG2

Manning ID

PKG2

Synonym

PRKGR2, cGKII, PKG2, PRKG2, PKG2/PRKG2

UniProt

Q13237 (KGP2_HUMAN)

Kinase Type

Protein kinase

Kinase Group

AGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-GSK3(14-27), ATP

Reaction

RBER-GSK3(14-27) + 33P-ATP = 33P-RBER-GSK3(14-27) + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 1
Sorafenib 10000
Sunitinb 5500

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice PRKG2
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number

N/A

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