PTPRC/CD45 Phosphatase Assay Service

PTPRC/CD45 Phosphatase Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
PTPRC/CD45
Enzyme
Human PTPRC/CD45
Synonyms
Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200
Substrates
Fluorogenic substrate DiFMUP, 10 μM
Assay Properties
Reaction
Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
NSC-878773,600
PHPS1820
PTP1B Inhibitor20,200
Scientific Information
P08575 (http://www.uniprot.org/uniprot/P08575)
Screening Location
Malvern, USA
Reference Compound IC50 for PTPRC/CD45
Reference Compound IC50 for PTPRC/CD45