PTPRJ/CD148 Phosphatase Assay Service

PTPRJ/CD148 Phosphatase Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview

CAT#

PTPRJ/CD148 

Enzyme

Human PTPRJ/CD148 

Synonyms

Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase eta, Protein-tyrosine phosphatase receptor type J, Density-enhanced phosphatase 1, DEP1

Substrates

Fluorogenic substrate DiFMUP, 10 μM

Assay Properties

Reaction

Protein tyrosine phosphate + H₂O = protein tyrosine + phosphate

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (μM)
PTP1B Inhibitor 10.9
NSC87877 30.2

Scientific Information

Q12913 (https://www.uniprot.org/uniprotkb/Q12913)

Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website Phosphatase Assay Services for Drug Discovery

Reference Compound IC50 for PTPRJ/CD148

Reference Compound IC50 for PTPRJ/CD148