Renin Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Renin
Enzyme
Human Renin
Species
Human
Synonyms
Angiotensinogenase
Scientific Information
P00797 (https://www.uniprot.org/uniprotkb/P00797)
Assay Properties
Substrates
Fluorogenic peptide H-D-CHA-Ala-Arg-AMC, 50 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 |
|---|---|
| Aliskiren Hemifumarate | 1.1 nM |
| Pepstatin A | 49.9 µM |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays
Reference compound inhibition of Renin
PDF