Activity-based SETD2 Methyltransferase Assay for compound screening and profiling via radiometric HotSpotTM methyltranferase assay.
Histone-lysine N-methyltransferase SETD2, HIF-1, Huntingtin yeast partner B, Huntingtin-interacting protein 1, HIP-1, Huntingtin-interacting protein B, Lysine N-methyltransferase 3A, SET domain-containing protein 2, HYPB, KIAA1732, KMT3A, SET2
Oligo Nucleosomes, 0.05 mg/ml
SAM, 1 µM
S-adenosyl-L-[methyl-³H]methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N⁶-[methyl-³H]-L-lysine
Reference Compound IC50s
Malvern, PA, USA
More information can be found on our website Methyltransferase Assays.
Reference compound IC50 for SETD2