SMARCA2b-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human SMARCA2b bromodomain, His-tagged
BAF190B, BRM, SNF2L2
Thermal stability change after ligand binding
0.2 mg/ml (4.8 µM)
PFI3 - 4 (Purple) No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, and GSK2801)
More information can be found on our website Reader Domain Assay Services.