SMARCA4-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human SMARCA4 bromodomain, His-tagged
BRG1, BAF190A, Protein BRG-1, SNF2-beta
Thermal stability change after ligand binding
0.15 mg/ml (8.8 µM)
PFI3 - 6 (Purple) No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, and GSK2801)
More information can be found on our website Reader Domain Assay Services.