SP100-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human SP100 bromodomain, GST-tagged
Nuclear dot-associated Sp100 protein
Thermal stability change after ligand binding
0.1 mg/ml (2.08 µM)
RVX-208 - 1 (Purple)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.