SP100-His Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human SP100 bromodomain, His-tagged
Nuclear dot-associated Sp100 protein
Thermal Stability Assay (TSA)
0.125 mg/ml (5.2 µM)
No stabilization was observed in the presence of control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.