SP110c-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human SP110c bromodomain, GST-tagged
Interferon-induced protein 41/75, Speckled 110 kDa, Transcriptional coactivator Sp110
Thermal stability change after ligand binding
0.1 mg/ml (2.1 µM)
No stabilization was observed in the presence of control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.