SP140L Bromodomain Assay Service (AlphaScreen)

SP140L-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview
CAT#

SP140L-His

Enzyme

Human SP140L-His

Synonyms

Nuclear body protein SP140-like protein

Substrates

Histone H3 peptide (1-21) K9/14Ac

Assay Properties
Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
JQ-1 62,000
SGC-CBP30 140,000
Scientific Information

Q9H930 (http://www.uniprot.org/uniprot/Q9H930)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for SP140L

Reference Compound IC50 for SP140L