SRPK1 Kinase Activity Assay Service

Activity-based SRPK1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

SRPK1

Enzyme

Human SRPK1, wt

HGNC

SRPK1

Manning ID

SRPK1

Synonym

SFRSK1, SRPK1

UniProt

Q96SB4 (SRPK1_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

MBP, ATP

Reaction

MBP + 33P-ATP = 33P-MBP + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 2300
Sorafenib 10000
Sunitinb 100000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice SRPK1
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – SRPK1
(Activity verified by 33PanQinaseTM-Assay)

Product Number

0434-0000-1

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