SRPK2 Kinase Assay Service

Activity-based SRPK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
SRPK2
Enzyme
Human SRPK2
HGNC
SRPK2
Synonym
SFRSK2
Substrates
Peptide substrate, [GRSRSRSRSR], 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine420
Ro 31-82201,400
GW 507411,000
H-89>100,000
Rottlerin>100,000
Scientific Information
P78362 (http://www.uniprot.org/uniprot/P78362)
Screening Location
Malvern, USA
Reference compound IC50 for SRPK2
Reference compound IC50 for SRPK2