SSTK/TSSK6 Kinase Assay Service

Activity-based SSTK/TSSK6 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
SSTK/TSSK6
Enzyme
Human SSTK/TSSK6
HGNC
TSSK6
Synonym
FLJ24002, SSTK
Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine160
Ro 31-82207,400
GW 507465,000
H-89>100,000
Rottlerin>100,000
Scientific Information
Q9BXA6 (http://www.uniprot.org/uniprot/Q9BXA6)
Screening Location
Malvern, USA
Reference compound IC50 for SSTK/TSSK6
Reference compound IC50 for SSTK/TSSK6