Activity-based STK17B kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
STK17B
Enzyme
Human STK17B, wt
HGNC
STK17B
Manning ID
DRAK2
Synonym
DRAK2
UniProt
O94768 (ST17B_HUMAN)
Kinase Type
Protein kinase
Kinase Group
CAMK
Assay Properties
Assay Format
33PanQinaseTM
Substrates
MRCL3, ATP
Reaction
MRCL3 + 33P-ATP = 33P-MRCL3 + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 11 |
| Sorafenib | 100000 |
| Sunitinb | 260 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | STK17B |
| 345 wt Profiler | No |
| 345 IC50 wt Profiler | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein |
Yes; ProQinaseTM – STK17B |
| Product Number |
1504-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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