STK25/YSK1 Kinase Assay Service

Activity-based STK25/YSK1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
STK25
Enzyme
Human STK25
HGNC
STK25
Synonym
YSK1, SOK1
Substrates
MBP (Myelin Basic Protein), 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine23.6
Ro 31-8220150
GW507435,000
H-8957,000
Scientific Information
O00506 (http://www.uniprot.org/uniprot/O00506)
Screening Location
Malvern, USA
Reference compound IC50 for STK25/YSK1
Reference compound IC50 for STK25/YSK1