STK32c/YANK3 Kinase Assay Service

Activity-based STK32c/YANK3 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
STK32C/YANK3

Enzyme
Human STK32C/YANK3

HGNC
STK32C

Synonym
YANK3

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 170
Ro 31-8220 5,600
GW 5074 >100,000
H-89 30,000
Rottlerin >100,000
Scientific Information
Q86UX6 (http://www.uniprot.org/uniprot/Q86UX6)

Screening Location
Malvern, USA

Reference compound IC50 for STK32C/YANK3
Reference compound IC50 for STK32C/YANK3