STK38/NDR1 Kinase Assay Service

Activity-based STK38/NDR1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
STK38/NDR1

Enzyme
Human STK38/NDR1

HGNC
STK38

Synonym
NDR1

Substrates
Peptide substrate, [KKRNRRLSVA], 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 0.9
Ro 31-8220 297
GW 5074 7,100
H-89 140
Rottlerin >100,000
Scientific Information
Q15208 (http://www.uniprot.org/uniprot/Q15208)

Screening Location
Malvern, USA

Reference compound IC50 for STK38/NDR1
Reference compound IC50 for STK38/NDR1