STK38L/NDR2 Kinase Assay Service

Activity-based STK38L/NDR2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
STK38L/NDR2

Enzyme
Human STK38L/NDR2

HGNC
STK38L

Synonym
NDR2

Substrates
Peptide substrate, [KKRNRRLSVA], 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 1.4
Ro 31-8220 1,750
GW 5074 22,000
H-89 810
Rottlerin >50,000
Scientific Information
Q9Y2H1 (http://www.uniprot.org/uniprot/Q9Y2H1)

Screening Location
Malvern, USA

Reference compound IC50 for STK38L/NDR2
Reference compound IC50 for STK38L/NDR2