STK38L/NDR2 Kinase Assay Service

Activity-based STK38L/NDR2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
STK38L/NDR2
Enzyme
Human STK38L/NDR2
HGNC
STK38L
Synonym
NDR2
Substrates
Peptide substrate, [KKRNRRLSVA], 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine1.4
Ro 31-82201,750
GW 507422,000
H-89810
Rottlerin>50,000
Scientific Information
Q9Y2H1 (http://www.uniprot.org/uniprot/Q9Y2H1)
Screening Location
Malvern, USA
Reference compound IC50 for STK38L/NDR2
Reference compound IC50 for STK38L/NDR2