TAF1-2-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human TAF1-2 bromodomain, GST-tagged
Transcription initiation factor TFIID subunit 1; p250, TAFII-250, Cell cycle gene 1 protein
Thermal stability change after ligand binding
0.1 mg/ml (2.3 µM)
Bromosportine - 2 (Blue) No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, SGC-CBP30, BET151, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.