TAF1-2 Bromodomain Assay Service (AlphaScreen)

TAF1-2-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview
CAT#

TAF1-2-His

Enzyme

Human TAF1-2-His

Synonyms

Transcription initiation factor TFIID subunit 1-Bromodomain 2, Cell cycle gene 1 protein, BA2R, CCG1, CCGS, TAF2A

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties
Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
Bromosporine 22
SGC-CBP30 12,000
GSK2801 2,600
Scientific Information

P21675 (http://www.uniprot.org/uniprot/P21675)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for TAF1-2

Reference Compound IC50 for TAF1-2