TAF1-2-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
TAF1-2-His
Enzyme
Human TAF1-2-His
Synonyms
Transcription initiation factor TFIID subunit 1-Bromodomain 2, Cell cycle gene 1 protein, BA2R, CCG1, CCGS, TAF2A
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Bromosporine | 22 |
| SGC-CBP30 | 12,000 |
| GSK2801 | 2,600 |
Scientific Information
P21675 (http://www.uniprot.org/uniprot/P21675)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for TAF1-2
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