TAF1L-Tndm-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human TAF1L-T bromodomain, GST-tagged
TAF(II)210, TBP-associated factor 1-like, TBP-associated factor 210 kDa, Transcription initiation factor TFIID 210 kDa subunit
Thermal stability change after ligand binding
0.1 mg/ml (1.7 µM)
GSK2801 - 1.5 (Yellow)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, Bromosporine, SGC-CBP30, BET151, RVX-208, and PFI3)
More information can be found on our website Reader Domain Assay Services.