TESK1 Kinase Assay Service

Activity-based TESK1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
TESK1
Enzyme
Human TESK1
HGNC
TESK1
Synonym
TESK1
Substrates
Cofilin 2, 3 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine260
Ro 31-822022,000
GW 50747,500
H-89>100,000
Rottlerin>100,000
Scientific Information
Q15569 (http://www.uniprot.org/uniprot/Q15569)
Screening Location
Malvern, USA
Reference compound IC50 for TESK1
Reference compound IC50 for TESK1