TLK2 Kinase Assay Service

Activity-based TLK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
TLK2
Enzyme
Human TLK2
HGNC
TLK2
Synonym
MGC44450, PKU-ALPHA
Substrates
Casein, 1 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine5.7
Ro 31-82202,500
Scientific Information
Q86UE8 (http://www.uniprot.org/uniprot/Q86UE8)
Screening Location
Malvern, USA
Reference compound IC50 for TLK2
Reference compound IC50 for TLK2