TLK2 Kinase Assay Service

Activity-based TLK2 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
TLK2

Enzyme
Human TLK2

HGNC
TLK2

Synonym
MGC44450, PKU-ALPHA

Substrates
Casein, 1 mg/ml
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Scientific Information
Q86UE8 (http://www.uniprot.org/uniprot/Q86UE8)

Screening Location
Malvern, USA

Reference compound IC50 for TLK2