TMPRSS2 Protease Assay Service

TMPRSS2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview

CAT#

TMPRSS2

Enzyme

Human TMPRSS2

Synonym

Transmembrane protease serine 2, Serine protease 10, PRSS10, TMPS2

Substrates

Fluorogenic peptide [Boc-Gln-Ala-Arg-AMC], 25 µM

Assay Properties

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Nafamostat Mesylate 0.024
Camostat Mesylate 0.31
FOY 251 7.6
Gabexate Mesylate (GM) 25
Bromhexine hydrochloride (BHH) >100,000

 

Scientific Information

Screening Location

Malvern, PA, USA

Further information

More information can be found on our website Protease Assay Services.

Reference compound IC50 for TMPRSS2

TMPRSS2 reference compound IC50