TRKA (G667S) Kinase Assay Service

Activity-based TRKA (G667S) kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
TRKA (G667S)

Enzyme
Human TRKA (G667S)

HGNC
NTRK1 (G667S)

Synonym
MTC, TRK, TRK1

Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Scientific Information
P04629 (http://www.uniprot.org/uniprot/P04629)

Screening Location
Malvern, USA

Reference compound IC50 for TRKA (G667S)