TRPM7/CHAK1 Kinase Assay Service

Activity-based TRPM7/CHAK1 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
TRPM7/CHAK1

Enzyme
Human TRPM7/CHAK1

HGNC
TRPM7

Synonym
CHAK1

Substrates
MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Scientific Information
Q96QT4 (http://www.uniprot.org/uniprot/Q96QT4)

Screening Location
Malvern, USA

Reference compound IC50 for TRPM7/CHAK1