Tryptase alpha/beta-1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Tryptase alpha/beta-1
Enzyme
Tryptase alpha/beta-1
Species
Human recombinant
Synonyms
TPS1, TPS2, TPSB1
Scientific Information
Q15661.1 (https://www.ncbi.nlm.nih.gov/protein/Q15661.1)
Assay Properties
Substrates
Fluorogenic peptide Z-GPR-AMC, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Gabexate Mesylate | 11.4 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays
Reference compound inhibition of Tryptase alpha/beta-1
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