TSSK2 Kinase Assay Service - Reaction Biology

Activity-based TSSK2 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

TSSK2

Enzyme

Human TSSK2

HGNC

TSSK2

Synonym

DGS-G, SPOGA2, FLJ38613

Substrates

Peptide substrate, [KKKVSRSGLYRSPSMPENLNRPR], 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q96PF2 (http://www.uniprot.org/uniprot/Q96PF2)

Screening Location

Malvern, USA

Reference compound IC50 for TSSK2