Activity-based TSSK3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
TSSK3
Enzyme
Human TSSK3, wt
HGNC
TSSK3
Manning ID
TSSK3
Synonym
TSSK3, SPOGA3, STK22C, STK22D
UniProt
Kinase Type
Protein kinase
Kinase Group
CAMK
Assay Properties
Assay Format
33PanQinaseTM
Substrates
4xChocktide, ATP
Reaction
Substrate + 33P-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 200 |
| Sorafenib | 50000 |
| Sunitinib | >100000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | TSSK3 |
| wt Profiler Panel | Yes |
| IC50 wt Profiler Panel | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – TSSK3 (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 2060-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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