Activity-based TTBK1 aa1-480 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
TTBK1 aa1-480
Enzyme
Human TTBK1 aa1-480, wt
HGNC
TTBK1 (aa1-480)
Manning ID
TTBK1
Synonym
BDTK, KIAA1855, RP3-330M21.4, TTBK1, TTBK1 aa1-480
UniProt
Q5TCY1 (TTBK1_HUMAN)
Kinase Type
Protein kinase
Kinase Group
CK1
Assay Properties
Assay Format
33PanQinaseTM
Substrates
RB-CTF, ATP
Reaction
RB-CTF + 33P-ATP = 33P-RB-CTF + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 64000 |
| Sorafenib | 10000 |
| Sunitinb | 100000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | TTBK1 aa1-480 |
| 345 wt Profiler | No |
| 345 IC50 wt Profiler | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein |
Yes; ProQinaseTM – TTBK1 aa1-480 |
| Product Number |
1731-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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